apalutamide will reduce the extent or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications which have been CYP3A4 substrates can result in reduced publicity to those medications.Commence typing to retrieve looku